Potential for Reduced Dependence and Abuse Liability
Introduction to Lower Risk of Respiratory Depression Compared to Traditional Opioids Traditional opioids such as morphine, oxycodone, and fentanyl have long been the cornerstone of moderate to severe pain management. However, their effectiveness is overshadowed by a significant safety concern: respiratory depression, a potentially life-threatening side effect that occurs when these drugs suppress the brain’s drive to breathe. This risk has fueled the ongoing opioid crisis, as respiratory depression remains a leading cause of overdose-related fatalities.
